Mechanism of Action:
Semax is known to stimulate neurotrophic factors in the central nervous system, namely Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF). It further appears to impact serotonin, dopamine, and enkephalin signaling.
Notable Studies:
· Semax in the treatment of glaucomatous optic neuropathy in patients with normalized ophthalmic tone
· The efficacy of semax in the treatment of patients at different stages of ischemic stroke
· Synthetic ACTH analog Semax displays nootropic‐like activity in humans
What is Semax?
Semax is a synthetic peptide that was first developed by Russian researchers in the 1980s. It is authorized in Russia and Ukraine for indications including ischemic brain stroke, encephalopathy, optic nerve atrophy, and cognitive disorders such as dementia.
Research suggests that Semax may offer potential benefits to patients suffering from a variety of neurological conditions, including Alzheimer's, traumatic brain injury (TBI), and stroke.
Semax is an analog of the ACTH(4-10) peptide, the latter a fragment of adrenocorticotropic hormone (ACTH). ACTH is a hormo ...
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